The findings were striking: Cognitive Decline: Participants with higher UPF consumption exhibited a more rapid decline in cognitive functions, including memory, attention, and executive functioning. This suggests that UPFs may accelerate brain aging and impair cognitive abilities. Brain Structure Changes: MRI scans revealed that individuals with diets high in UPFs had significant changes in brain structure. These changes included reduced gray matter volume and compromised white matter integrity,
0:05
The findings were striking: Cognitive Decline: Participants wi…
2.3K viewsAug 10, 2024
FacebookDavid Perlmutter, M.D.
Is your gut health putting your brain at risk? I’m breaking down how changes in the gut can trigger inflammation—one of the key drivers of cognitive decline. Let’s discuss ☝️ | David Perlmutter, M.D.
0:41
Is your gut health putting your brain at risk? I’m breaking down how ch…
3.3K viewsMar 19, 2025
FacebookDavid Perlmutter, M.D.
You’ve heard that exercise supports your brain health, and that’s true. However, new research shows it’s not the full story, and I want you to have all the facts. A study from the University of Rochester found that even people who exercise regularly still face increased Alzheimer’s risk if they spend too much of their day sitting. This risk is even more significant for those who carry the APOE4 gene variant. The takeaway I have for you is this: Movement throughout your day matters. You don’t nee
1:08
You’ve heard that exercise supports your brain health, and that’s true. …
6.3K views8 months ago
FacebookDavid Perlmutter, M.D.
Could too much sitting around be threatening your brain health? If you spend most of your day sitting, I want to remind you that change doesn’t have to be big to be meaningful. Movement isn’t just for your body, it’s nourishment for your brain. When you move, you’re creating chemistry that supports clarity, mood, and long-term brain health. I encourage you to make a small shift in your movement pattern today. It can make a lasting difference in how you think and feel tomorrow. | David Perlmutter
1:22
Could too much sitting around be threatening your brain health? If y…
2.7K views5 months ago
FacebookDavid Perlmutter, M.D.
We know the gut-brain connection is important, but your oral health is proving to be just as critical. Research shows that periodontal disease (gum disease) increases Alzheimer’s risk by triggering inflammation that activates brain immune cells called microglial cells. Simple steps like brushing twice a day, flossing, and maintaining overall oral health can help protect your brain. I cover this and more in my upcoming book, Brain Defenders — stay tuned! | David Perlmutter, M.D.
1:41
We know the gut-brain connection is important, but your oral health i…
4.1K views5 months ago
FacebookDavid Perlmutter, M.D.
I often get asked about antidepressants and their impact on brain health. Some studies suggest that certain commonly prescribed medications may increase the risk of dementia. For older adults, especially those at higher risk for Alzheimer’s due to age, sex, metabolic conditions, or family history, I encourage you to be aware of this research and discuss any concerns with your healthcare provider. I wrote about this topic on a recent blog post — read it here: https://drperlmutter.com/antidepressa
1:38
I often get asked about antidepressants and their impact …
4.9K views5 months ago
FacebookDavid Perlmutter, M.D.
Some of the most powerful chemicals for brain health are not found in a supplement bottle. They are made inside your own body. Your muscles create a group of compounds that support memory, protect neurons, and lower the risk of cognitive decline. These chemicals are released during movement, and they help explain why exercise has such a profound effect on long-term brain health. There is something incredibly empowering about knowing you can create this kind of support from within. All it takes i
1:05
Some of the most powerful chemicals for brain health are not …
14K views3 months ago
FacebookDavid Perlmutter, M.D.
I’m thrilled to announce the world premiere of Alzheimer’s - The Science of Prevention, where I, along with the world’s leading brain health experts have come together to reveal the secrets about what triggers brain disease and how to help protect yourself and loved ones from developing Alzheimer’s. This groundbreaking documentary series will premiere from July 17th - July 28th and each episode will be FREE to watch online for 24 hours. You can reserve your seat at the link below! EPISODE 1 - Th
3:24
I’m thrilled to announce the world premiere of Alzheimer’s - The Scie…
1.7M viewsJul 16, 2019
FacebookDavid Perlmutter, M.D.
Dr. David Perlmutter explains why good metabolism is the key to excellent brain health. | Lewis Howes
3:47
Dr. David Perlmutter explains why good metabolism is the key to exc…
151.5K viewsDec 2, 2024
FacebookLewis Howes
We discuss Brain Wash, the new book by David Perlmutter, M.D. and Dr. Austin Perlmutter. They expose how our health, our relationships, and even our thinking have been damaged by modern culture, and offer a practical plan for healing. Brain Wash is now available wherever books are sold: https://brainwashbook.com/ | Steven Masley
27:48
We discuss Brain Wash, the new book by David Perlmutter, M.D. an…
886 viewsJan 14, 2020
FacebookSteven Masley
How do we help the brain recover from the lasting effects of long COVID? This week on The Empowering Neurologist, I’m exploring the cutting-edge science of hyperbaric oxygen therapy with Dr. Amir Hadanny, Chief Medical Officer of @AvivClinics. We’re discussing how this therapy enhances mitochondrial function and offers new hope for people facing neurological challenges like long COVID, dementia, stroke, and more. Tune in here: https://youtu.be/t-PucwCpins | David Perlmutter, M.D.
1:24
How do we help the brain recover from the lasting effects of long C…
4.3K viewsDec 11, 2024
FacebookDavid Perlmutter, M.D.
Shift Immune Cells From Attack to Brain-Defense Mode | David Perlmutter MD
49:08
Shift Immune Cells From Attack to Brain-Defense Mode | David Perlm…
8.7K views2 months ago
theepochtimes.com
Why would a neurologist care about oral health? Because what’s happening in your mouth affects far more than just your teeth. It can influence your brain, heart, metabolism, and even blood pressure. Here’s the surprising part: some antibacterial mouthwashes may actually disrupt the good bacteria that help produce nitric oxide, a key player in insulin function and vascular health. The bottom line? Caring for your brain means paying attention to everyday habits that might seem unrelated. Oral care
1:48
Why would a neurologist care about oral health? Because what’s happ…
6.4K views9 months ago
FacebookDavid Perlmutter, M.D.
Fair to say that we all assume that aging is inevitable. In reality however, there is no biological law that says we must age. Over the years we've seen a variety of theories proposed to explain why we age including the accumulation of damage to our DNA, the damaging effects of chemicals called "free radicals,” changes in the function of our mitochondria, and so many others. Our guest today, Dr. David Sinclair, believes that aging is related to a breakdown of information. Specifically, he descri
1:00:19
Fair to say that we all assume that aging is inevitable. In reality howe…
10.8K viewsJan 24, 2021
FacebookDavid Perlmutter, M.D.
Today on The Empowering Neurologist: Dr. Emeran Mayer on the mind-gut connection, and how the hidden conversation within our bodies impacts our mood, our choices, and our overall health. http://bit.ly/29n1Iax | David Perlmutter, M.D.
39:16
Today on The Empowering Neurologist: Dr. Emeran Mayer o…
11.9K viewsJul 6, 2016
FacebookDavid Perlmutter, M.D.
Dr. David Perlmutter here to answer an important question from @louisanicola: How does chronic stress and inflammation impact the brain and our rate of getting Alzheimer’s disease? Stay tuned for Dr. Perlmutter’s question for Louisa! | David Perlmutter, M.D.
0:57
Dr. David Perlmutter here to answer an important question from @loui…
1.6K viewsAug 7, 2024
FacebookDavid Perlmutter, M.D.
Today on The Empowering Neurologist, I’m joined by Dr. Melissa Schilling, of New York University, to discuss the empowering topic of Alzheimer’s prevention. As you’re all well aware, this is a subject at the core of my work, and Dr. Schilling’s recent findings, on the role of blood sugar in brain health, could be a game changer. Hope you enjoy. http://www.drperlmutter.com/empowering-neurologist-david-perlmutter-md-dr-melissa-schilling/ | David Perlmutter, M.D.
19:57
Today on The Empowering Neurologist, I’m joined by Dr. Meli…
23.6K viewsJun 8, 2016
FacebookDavid Perlmutter, M.D.
By 2060, dementia cases are expected to double. While aging may play a role, lifestyle factors are just as critical—and that means there are things you can do today to protect your brain. ✅ Prioritize metabolic health: High blood sugar and insulin resistance increase your risk. Monitoring fasting insulin and wearing a continuous glucose monitor can help you stay on track. ✅ Move your body: Exercise is one of the most powerful ways to protect your brain and reduce risk. With no meaningful pharmac
1:19
By 2060, dementia cases are expected to double. While aging …
11.8K views11 months ago
FacebookDavid Perlmutter, M.D.
April is Parkinson’s Awareness Month—and while awareness is important, it’s time we shift the focus to prevention. Research continues to show that lifestyle choices can play a powerful role in reducing the risk of Parkinson’s. Let’s pay attention to the steps we can take now to help protect our brain health for the future. | David Perlmutter, M.D.
1:27
April is Parkinson’s Awareness Month—and while awareness is i…
1.6K views11 months ago
FacebookDavid Perlmutter, M.D.
Are you worried about memory loss? A new study confirms what I’ve been saying for decades: lifestyle changes such as exercise, diet, and social connection can improve cognitive function, even in people with genetic risk for Alzheimer’s. Our choices shape our brain’s future more than our genes do. Don’t take your power in your destiny for granted. | David Perlmutter, M.D.
1:29
Are you worried about memory loss? A new study confirms what …
8.8K views4 months ago
FacebookDavid Perlmutter, M.D.
Struggling with sleep? Poor REM sleep isn’t just about feeling tired—there’s a direct link to Alzheimer’s risk. A new study highlights this connection, and I’m sharing simple steps to improve your sleep hygiene and support brain health. | David Perlmutter, M.D.
1:07
Struggling with sleep? Poor REM sleep isn’t just about feeling tired…
4.6K viewsMar 17, 2025
FacebookDavid Perlmutter, M.D.
We don’t yet have meaningful treatments for Alzheimer’s or Parkinson’s that address the root cause. Research, however, continues to show that lifestyle choices can have a powerful influence on risk and progression. In a recent interview with @MedicalNewsToday, I shared insights on how metabolic and hormonal factors, along with neuroinflammation, may impact brain health. Read the report here: https://www.medicalnewstoday.com/articles/ibs-vitamin-d-deficiency-may-predict-alzheimers-parkinsons-dise
1:13
We don’t yet have meaningful treatments for Alzheimer’s or Park…
7.5K views6 months ago
FacebookDavid Perlmutter, M.D.
We often talk about nutrition, sleep, and stress, and rightfully so. Physical fitness, though, deserves just as much attention when it comes to protecting the brain. Cardiorespiratory fitness isn't just about heart health. It plays a critical role in regulating glucose, improving insulin function, and ultimately reducing risk for cognitive decline. Exercise is a non-negotiable part of brain preservation and the science keeps pointing us back to it. | David Perlmutter, M.D.
1:37
We often talk about nutrition, sleep, and stress, and rightfully so. Phys…
10.6K views10 months ago
FacebookDavid Perlmutter, M.D.
You might not expect this, but feeling lonely isn’t just an emotion—it can have an immediate and lasting impact on brain health, especially as we age. If you needed a reminder to call your aging family member or friend, listen to this 👆 | David Perlmutter, M.D.
1:00
You might not expect this, but feeling lonely isn’t just an emotio…
3.3K viewsDec 4, 2024
FacebookDavid Perlmutter, M.D.
Many sweeteners marketed as healthy can actually harm your metabolism. Splenda disrupts the gut microbiome, and agave nectar, although it sounds “natural,” is about 70 percent fructose. Fructose increases fat storage, reduces mitochondrial function, and contributes to insulin resistance. For anyone prioritizing metabolic and brain health, avoiding these sweeteners is a straightforward and powerful step. One sweetener I do recommend is allulose, which has a low or negligible effect on blood sugar
1:06
Many sweeteners marketed as healthy can actually harm your m…
10.5K views5 months ago
FacebookDavid Perlmutter, M.D.
I’m thrilled to share that I recently joined @LewisHowes on The School of Greatness podcast for a deep dive into the powerful connection between metabolism and brain health. As both a neurologist and someone who has personally felt the impact of Alzheimer’s in my family, this conversation holds a special place in my heart. We explored: ✨ How modern dietary habits are shaping our cognitive health. ✨ The groundbreaking research behind GLP-1 agonists. ✨ Practical steps to protect and even restore b
0:36
I’m thrilled to share that I recently joined @LewisHowes on The Sch…
97.1K viewsDec 18, 2024
FacebookDavid Perlmutter, M.D.
Imagine a therapy for Alzheimer’s that doesn’t involve invasive procedures or harsh side effects—just light and sound helping the brain heal itself. I recently spoke with Christian Howell of Cognito Therapeutics to explore their groundbreaking approach to restoring brain rhythms, reducing the toxic proteins that drive Alzheimer’s, and even potentially preventing cognitive decline. For families facing Alzheimer’s—or anyone wanting to be proactive about brain health—this research offers real hope
0:56
Imagine a therapy for Alzheimer’s that doesn’t involve invasive proc…
2.2K viewsJan 30, 2025
FacebookDavid Perlmutter, M.D.
One of the most powerful tools we have to protect our brains from Alzheimer's is right on our plates. A brain-healthy diet—rich in leafy greens, healthy fats, and antioxidants—can go a long way in reducing cognitive decline. Here’s one of my favorite recipes complete with brain-boosting ingredients: https://drperlmutter.com/recipe/greek-chicken-with-wilted-greens/ | David Perlmutter, M.D.
0:04
One of the most powerful tools we have to protect our brains from Al…
1.1K viewsNov 7, 2024
FacebookDavid Perlmutter, M.D.
Exercise isn’t just good for your body—it’s one of the most powerful tools for protecting brain health. In the latest episode of The Empowering Neurologist, I sit down with Austin Perlmutter, MD to explore the direct connection between muscle activity and brain function. We cover: ✅ How exercise protects against cognitive decline ✅ The best types of exercise for brain health ✅ Protein intake & supplements that enhance brain benefits Watch the full episode here: https://youtu.be/C9rijLbRZVM? | Da
1:18
Exercise isn’t just good for your body—it’s one of the most powerf…
6.4K viewsFeb 10, 2025
FacebookDavid Perlmutter, M.D.
What is Brain Wash? (Dr. David Perlmutter Explains) | Thrive Market
What is Brain Wash? (Dr. David Perlmutter Explains) | Thrive Market
13.9K viewsJan 17, 2020
YouTubeThrive Market
See more