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David Perlmutter, M.D.
We often talk about nutrition, sleep, and stress, and rightfully so. Physical fitness, though, deserves just as much attention when it comes to protecting the brain. Cardiorespiratory
David Perlmutter, M.D.. . We often talk about nutrition, sleep, and stress, and rightfully so. Physical fitness, though, deserves just as much attention when it comes to protecting the brain. Cardiorespiratory fitness isn't just about heart health. It plays a critical role in regulating glucose, improving insulin function, and ultimately ...
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Apr 6, 2023
Today’s Empowering Neurologist interview is with Lisa Mosconi, PhD. She is the associate director of the Alzheimer’s Prevention Clinic at Weil Cornell Medical College in New York. I think will really enjoy this interview and learn about her new book, Brain Food (https://amzn.to/2WblOLo), which not only looks at nutrition but also leverages the science of nutritional genomics, and even the emerging science relating to the role of the microbiome in brain health. The book provides recommendations t
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Jan 24, 2019
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My goal with The Grain Brain Whole Life Plan? To help you get healthy, for life. | David Perlmutter, M.D.
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Can a keto diet support mental health? I spoke with @georgiaedemd who co-authored the first inpatient study of the ketogenic diet for serious mental illness, developed the first medically accredited course in ketogenic diets for mental health, and is a recipient of the Baszucki Brain Research Fund's Metabolic Mind Award. During our conversation we discuss: ✅ The profound connection between food and mental health ✅ Why robust mental health begins with metabolic health ✅ Practical, science-backed
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You’ve heard that exercise supports your brain health, and that’s true. However, new research shows it’s not the full story, and I want you to have all the facts. A study from the University of Rochester found that even people who exercise regularly still face increased Alzheimer’s risk if they spend too much of their day sitting. This risk is even more significant for those who carry the APOE4 gene variant. The takeaway I have for you is this: Movement throughout your day matters. You don’t nee
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Is your gut health putting your brain at risk? I’m breaking down how changes in the gut can trigger inflammation—one of the key drivers of cognitive decline. Let’s discuss ☝️ | David Perlmutter, M.D.
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Mar 19, 2025
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We know the gut-brain connection is important, but your oral health is proving to be just as critical. Research shows that periodontal disease (gum disease) increases Alzheimer’s risk by triggering inflammation that activates brain immune cells called microglial cells. Simple steps like brushing twice a day, flossing, and maintaining overall oral health can help protect your brain. I cover this and more in my upcoming book, Brain Defenders — stay tuned! | David Perlmutter, M.D.
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I often get asked about antidepressants and their impact on brain health. Some studies suggest that certain commonly prescribed medications may increase the risk of dementia. For older adults, especially those at higher risk for Alzheimer’s due to age, sex, metabolic conditions, or family history, I encourage you to be aware of this research and discuss any concerns with your healthcare provider. I wrote about this topic on a recent blog post — read it here: https://drperlmutter.com/antidepressa
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