When a cell is confronted by stress, p53 is stabilized in the nucleus, where it initiates cellular responses through transcriptional activation or repression of distinct target genes that primarily ...

Post-translational modifications are modifications that occur on a protein, catalysed by enzymes, after its translation by ribosomes is complete. Post-translational modification generally refers to ...

President Donald Trump has moved swiftly to implement his policies across the federal government mainly with sweeping executive orders. His administration has been particularly focused on removing any ...

Most of our prior work focused on the Ubl protein SUMO as it is essential in budding yeast and its conjugation to substrates requires an enzyme cascade that involves fewer factors in comparison to the ...