Somatostatin, a signaling molecule produced by many inhibitory neurons in the brain, broadly dampens communication among a variety of cell types in the prefrontal cortex and promotes exploratory and ...

WEST LAFAYETTE, Ind. - A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity ...

Can eating fat be good for us? Some fatty acid molecules actually play a crucial role in maintaining our health and cellular functions. By the early twentieth century, scientists and doctors widely ...

Although USP22 has been associated with IFN signaling and ISG expression upon viral infections, the mechanisms underlying USP22 priming of PRRs and IFN signaling in native, uninfected environments ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug ...

Now UAB researchers, led by Guanlan Xu, Ph.D., and Shalev drilled down further into the mechanism underlying verapamil’s beneficial effect. In a paper published in Diabetes, they show that, in Type 1 ...

Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or ...

Scientists at EPFL have created a scalable 3D organoid model that captures key features of early limb development, revealing how a specialized signaling center shapes both cell identity and tissue ...

Yale School of Medicine (YSM) scientists have discovered a molecular difference in the brains of autistic people compared to their neurotypical counterparts. Autism is a neurodevelopmental condition ...