Loss and dysfunction of synapses have been linked to age-related cognitive decline and observed in Alzheimer's and other ...

The complexity of the human brain is unparalleled. Fortunately, thanks to constant progress in neuroscience over the past decades, we have started to make some sense of the human brain. For instance, ...

Specific brain cells known as layer 5 pyramidal neurons play a vital role in how our brains process information. Research by the team of Prof. Joris de Wit (VIB-KU Leuven) and colleagues highlights ...

Schematic representation of axonal transport vesicles (blue) carrying presynaptic proteins (SV and AZ proteins). Kinesin motor proteins (KIF1A) attach these vesicles and carry them along the axons to ...

Co-written with Jai Liester. Silent synapses represent one of neuroscience's most fascinating discoveries—connections between neurons that lie dormant until activated by specific triggers. These ...

A team of experimental neurobiologists and theoretical biologists has managed to solve a mystery that has been baffling scientists for decades. They have been able to determine the nature of the ...

A team that has used two-photon imaging technology to show the creation and elimination of synapses between neurons in the brains of live mice. A University of Minnesota Twin Cities researcher is part ...

Neuroscience discoveries of the biological brain are important not only because they may lead to novel therapeutics to treat brain disorders, but also because they may serve as models for artificial ...

Learning lots of new information as a baby requires a pool of ready-to-go, immature connections between nerve cells to form memories quickly. Called silent synapses, these connections are inactive ...

In a study published in the European Journal of Neuroscience, researchers explored amyloid-beta (Aβ)-driven neuroinflammation and synapse loss in feline cognitive dysfunction syndrome (CDS). They also ...