A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics.

For most proteins, structure is function. The complex three-dimensional shapes that proteins adopt create folds and pockets that can accomplish the remarkably improbable: driving chemical reactions ...

Recent advances in computational biology have revolutionised the field of protein structure and function prediction. Traditionally, determining the three‐dimensional architecture of a protein from its ...

A new LMU study shows how proteins function reliably even without a stable 3D structure—and the crucial importance not only of short sequence motifs, but also of chemical characteristics.

For years, biomolecular condensates were thought to be simple, liquid-like droplets with little internal organization. New ...

The genomes of phages—viruses that infect bacteria—are largely composed of "dark matter": genes that encode proteins whose functions remain unknown. Less than four years ago, a team led by Prof. Rotem ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, intriguingly, many of the most important proteins involved in gene ...

Protein activity can be precisely regulated via subtle changes in temperature using heat-sensitive switches. Underlying this capability is a novel modular design strategy developed by researchers at ...

Today (September 21), the Lasker Foundation announced this year’s award winners. John Jumper, a computational biologist at DeepMind, and Demis Hassabis, cofounder and CEO at DeepMind, were awarded the ...

Proteins, the natural molecules that carry out key cellular functions within the body, are the building blocks of all diseases. Characterizing proteins can reveal the mechanisms of a disease, ...

In Greek mythology, Proteus, son of Poseidon and prophetic shepherd of sea-beasts, could foretell the future. The elusive sea god was difficult to capture as he assumed many forms—a lion, a serpent, ...