Potassium KCNQ2/3 channels are crucial for suppressing the excitability of brain cells, or neurons. When these channels don't work properly, they can cause specific types of epilepsy like benign ...
Researchers discover that KCNQ2/3 potassium channels must be functional to reach their proper location in the brain, with major implications for treating epilepsy.
A key approach to understanding the brain is to observe the behavioral effects of turning on specific populations of neurons. One of the most popular approaches to controlling neuronal activity in ...
ATP-sensitive potassium (KATP) channels are critical molecular sensors that link cellular metabolism with membrane excitability. Composed of inward rectifier potassium channel subunits coupled to ...
Potassium channels are essential membrane proteins that enable the selective and rapid transport of K⁺ ions, a process fundamental to cellular excitability and signal transduction. Recent research has ...
Molecular Devices, at SLAS 2015, launched a homogeneous, no-wash assay to measure ligand- and voltage-gated potassium channel activity. The FLIPR® Potassium Assay Kit uses a novel thallium-sensitive ...
Clinical trial results provide rationale for continued study of the KCNQ type of ion channel. Researchers from the Icahn School of Medicine at Mount Sinai have identified a drug that works against ...
Ion selectivity is an important property of cell membrane ion channels. For example, potassium ion channels are more permeable to potassium ions than to sodium ions. The mechanism underlying the ready ...