A new study has uncovered how the commonly used local anesthetic drug, lidocaine, activates bitter taste receptors to exert an anti-cancer effect in head and neck cancers. Given its low cost and ready ...

Local anesthetics have transformed clinical practice by enabling a broad range of minor and major procedures with minimal discomfort. Although adverse reactions are frequently reported, genuine ...

A new study published in the Feb. 2012 issue of Anesthesiology found that the type of lipid emulsion used to reverse toxicity of local anesthetics may change the effectiveness of the reversal, ...

The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

All current local anesthetics block sensory signals—pain—but they also interrupt motor signals, which can be problematic. For example, too much epidural anesthesia can prevent mothers in labor from ...

Advocates urge clinicians to consult with elective surgery patients about local anesthetics shortages, the potential health risks, and alternative forms of pain management. A global shortage of local ...

Does providing postoperative local anesthetic in addition to intravenous analgesics improve comfort in children undergoing dental surgery under general anesthesia? Research presented on March 24 at ...

Deaths from lidocaine poisonings more than doubled since 2010, calls to poison control centers suggested. Calls about local anesthetic poisonings decreased by 23%, mainly due to fewer non-lidocaine ...

Between two types of local anesthetics, there are 132 in short supply and 13 available, according to the American Society of Health-System Pharmacists. Twenty bupivacaine injections from Pfizer are ...

Age, new comorbidities, inflammation, cognitive reserve, and changes in anxiety levels alter drug effects and recovery.