When blood glucose levels rise, beta cells in pancreatic islets release insulin into the bloodstream. Insulin triggers glucose uptake in a variety of tissues including fat and muscle. Glucose and ...

Researchers have devised the right conditions to grow vascularized stem cell islets. The image shows vasculature (red) tightly wrapped around insulin-producing cells (green) in the islets (blue).

The currently approved islet-transplant method infuses islets into a vein in the liver. This invasive procedure requires the long-term use of immune-suppressing drugs to prevent islet rejection, ...

Diabetes mellitus (DM) is a metabolic disease characterized by pancreatic malfunctional and poor production of insulin. Imagine your pancreas is a factory for insulin, a key hormone that keeps your ...

Scientists in Shanghai have developed a potentially groundbreaking treatment for diabetes that targets the root cause of the disease rather than just its symptoms, offering hope for a functional cure.

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance, published in ...