Competition between Quaking and SF1 for a subset of ACUAA intron branch sites influences alternative splicing in different tissues and organisms.

We are far from understanding all the rules that govern the process of RNA splicing and defining the sequence information that governs intron definition. In the September 25 Proceedings of the ...

The completed sequencing of entire bacterial genomes and recent advances in genomics has allowed the identification of many genes. While several genes have been characterized, the function of the ...

Within multi-exon genes, after introns are removed, the exons must be spliced back together. Splice-enhancer domains (exon sequences near the intron–exon boundary) help to ensure that this happens ...

Introns are perhaps one of our genome's biggest mysteries. They are DNA sequences that interrupt the sensible protein-coding information in your genes, and need to be 'spliced out.' Although you may ...

Regions of the genome with repetitive sequences are difficult to selectively edit because it’s hard to control which of the repeated sections will be edited. Ribosomes, the molecular machines that ...