For years, biomolecular condensates were thought to be simple, liquid-like droplets with little internal organization. New ...
Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...
Even after decades of peering into cells, biologists are still finding surprises. In a twist, researchers at the University of Virginia and the National Institutes of Health uncovered a new organelle, ...
Orthohantaviruses, such as the Puumala virus, are widespread in Europe, causing flu-like illnesses and severe kidney damage in those infected. It is increasingly considered a zoonotic threat.
RAB7A plays a central role in the final stages of autophagy, facilitating autophagosome-lysosome fusion, lysosome positioning, and cargo degradation. Its activation by guanine nucleotide exchange ...
Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...
Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...
A sac-like structure formed by day 10 in over 90% of the PGAs. These gradually expanded in size over 90 days, without being given any further signals. The cell composition in the models showed ...
Herpes simplex virus partially liquefies the tightly packed, gel-like interior of human cell nuclei to copy itself faster, a new study shows. The research centers on how the nucleus of each human cell ...