Proteins that bind to DNA are ubiquitous in biology. The ability of these proteins to bind to specific DNA sequences with high affinity is often central to their function, and it is not uncommon for a ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

MADISON — Using computer simulations, a team of University of Wisconsin-Madison researchers has identified some of the pathways through which single complementary strands of DNA interact and combine ...

A team of investigators at Carnegie Mellon University has formed the first hybrid quadruplex of peptide nucleic acids, or PNAs, with DNA, the genetic code. This result opens new opportunities to study ...

Cockayne syndrome (CS) is a rare disease that causes short stature, premature aging (progeria), severe photosensitivity, and moderate to severe learning delay. A new study by researchers from the ...

Researchers in China have developed a new method that allows them to insert long stretches of DNA into a genome. The process, named GRAND editing, is one of a handful of new systems aimed at using two ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

Next-generation sequencing (NGS) has made analyzing DNA faster and cheaper, with effects felt in the lab, clinic, and beyond. A set of newly-launched technologies are offering a twist on the chemistry ...

DNA can signal the presence of or predisposition to a slew of diseases, including cancer. The ability to flag down these clues, known as biomarkers, allows medical professionals to make critical early ...