Credit: Shutterstock A naturally occurring compound in rice bran may play an unexpected role in regulating intestinal ...

Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor effects and also found to have anti-malarial effects. Now, researchers have ...

Researchers have developed a compound that relieves pain in mice but doesn't affect the brain, thereby avoiding mind-altering side effects and abuse potential. The custom-designed molecule, derived ...

Although it has long been used in traditional Chinese medicine to treat conditions including rheumatoid arthritis and psoriasis, regulatory bodies have warned against the use of celastrol due to the ...

Promoting pyroptosis—an inflammatory form of programmed cell death—has become a promising treatment strategy for cancer. In research published in The FASEB Journal, investigators purified a long-chain ...

The effectiveness of non-clinical drug safety predictions is enhanced by the adoption of three-dimensional (3D) cellular models. 3D bioprinting enables the generation of complex models with spatial ...

Researchers at WashU Medicine and Stanford University developed a compound that relieves pain in mice but doesn't affect the brain, thereby avoiding mind-altering side effects and abuse potential. The ...