T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial ...

Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...

Inositol phosphates are crucial secondary messengers that modulate a wide range of cellular processes, from energy metabolism to gene expression. These molecules, particularly inositol pyrophosphates, ...

A wave of recent neuroscience research has identified specific molecular and cellular mechanisms through which alcohol disrupts signaling between brain cells, offering a sharper picture of how ...

SMART, a new software package, can make studying signaling processes significantly easier. Results could accelerate research in fields across the life sciences, such as systems biology, pharmacology ...

Discover how targeted red and near-infrared light therapies influence mitochondrial biology, cellular repair pathways, and emerging clinical treatments across multiple health systems.

Severe bacterial pneumonia remains a major cause of death in critically ill patients, largely due to impaired early immune responses. New research reveals that butyric acid, a metabolite produced by ...

Background High serum levels of interleukin 6 (IL-6) predict poor prognosis in intrahepatic cholangiocarcinoma (iCCA), a malignancy that often develops in a chronically inflamed milieu . Here, tumour ...