The effectiveness of non-clinical drug safety predictions is enhanced by the adoption of three-dimensional (3D) cellular models. 3D bioprinting enables the generation of complex models with spatial ...

The origin of many diseases begins at the cellular level and involves multiple molecular interactions. However, previous ...

Advanced 3D cell models recreate the complexity of human tissues, enabling researchers to examine tumor progression, probe neurological disorders, and assess therapeutic candidates. By capturing the ...

In a major leap forward for genetic and biomedical research, two scientists at the University of Missouri have developed a powerful new artificial intelligence tool that can predict the 3D shape of ...

Researchers developed a microfluidic chip with 3D-printed microstructures that moves droplets precisely, captures cells efficiently, and quickly forms cell spheroids for improved lab-grown tissue ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

Advancing neurological disorder research requires model systems that more accurately reflect the human brain. 3D cell cultures, such as organoids and spheroids, have emerged as game-changers by better ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., at UMass Chan Medical School, has extensively mapped and analyzed the three ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...